Aurélie Robin est ingénieure en recherche biomédicale au sein de l’unité INSERM U1313 sur le site du pôle de Biologie Santé. Ses projets de recherche s’articulent autour des mécanismes immunitaires impliqués dans l’inflammation et la réparation tissulaire en transplantation rénale et hépatique chez l’homme et en modélisation animale. Ces travaux de recherche ont pour but d’identifier des cibles thérapeutiques afin d’améliorer la survie des greffons après transplantation (Axe 3).

Biologie cellulaire, biologie moléculaire, histologie, culture cellulaire (primaires et lignées), cytométrie en flux, expérimentation animale, biochimie.

• Early activation and recruitment of invariant natural killer T cells during liver ischemia-reperfusion: the major role of the alarmin interleukin-33.
  Robin A, Mackowiak C, Bost R, Dujardin F, Barbarin A, Thierry A, Hauet T, Pellerin L, Gombert JM, Salamé E, Herbelin A, Barbier L. Front Immunol. 2023 May 9;14:1099529. doi: 10.3389/fimmu.2023.1099529. eCollection 2023. PMID: 37228593
• Endogenous Interleukin-33 Acts as an Alarmin in Liver Ischemia-Reperfusion and Is Associated With Injury After Human Liver Transplantation.
  Barbier L, Robin A, Sindayigaya R, Ducousso H, Dujardin F, Thierry A, Hauet T, Girard JP, Pellerin L, Gombert JM, Herbelin A, Salamé E. Front Immunol. 2021 Sep 21;12:744927. doi: 10.3389/fimmu.2021.744927. eCollection 2021. PMID: 34621275
• [Ischemia-reperfusion injury after kidney transplantation].
  Dufour L, Ferhat M, Robin A, Inal S, Favreau F, Goujon JM, Hauet T, Gombert JM, Herbelin A, Thierry A. Nephrol Ther. 2020 Nov;16(6):388-399. doi: 10.1016/j.nephro.2020.05.001. Epub 2020 Jun 19. PMID: 32571740
• Interleukin-1 Family Cytokines: Keystones in Liver Inflammatory Diseases.
  Barbier L, Ferhat M, Salamé E, Robin A, Herbelin A, Gombert JM, Silvain C, Barbarin A. Front Immunol. 2019 Aug 27;10:2014. doi: 10.3389/fimmu.2019.02014. eCollection 2019. PMID: 31507607
• The Impact of Invariant NKT Cells in Sterile Inflammation: The Possible Contribution of the Alarmin/Cytokine IL-33.
  Ferhat MH, Robin A, Barbier L, Thierry A, Gombert JM, Barbarin A, Herbelin A. Front Immunol. 2018 Oct 15;9:2308. doi: 10.3389/fimmu.2018.02308. eCollection 2018. PMID: 30374349.
• Endogenous IL-33 Contributes to Kidney Ischemia-Reperfusion Injury as an Alarmin. Ferhat M, Robin A, Giraud S, Sena S, Goujon JM, Touchard G, Hauet T, Girard JP, Gombert JM, Herbelin A, Thierry A. J Am Soc Nephrol. 2018 Apr;29(4):1272-1288. doi: 10.1681/ASN.2017060650. Epub 2018 Feb 7. PMID: 29436517
• The Hypothesis of the Human iNKT/Innate CD8(+) T-Cell Axis Applied to Cancer: Evidence for a Deficiency in Chronic Myeloid Leukemia. Jacomet F, Cayssials E, Barbarin A, Desmier D, Basbous S, Lefèvre L, Levescot A, Robin A, Piccirilli N, Giraud C, Guilhot F, Roy L, Herbelin A, Gombert JM. Front Immunol. 2017 Jan 16;7:688. doi: 10.3389/fimmu.2016.00688. eCollection 2016. PMID: 28138330
• Evidence for eomesodermin-expressing innate-like CD8(+) KIR/NKG2A(+) T cells in human adults and cord blood samples. Jacomet F, Cayssials E, Basbous S, Levescot A, Piccirilli N, Desmier D, Robin A, Barra A, Giraud C, Guilhot F, Roy L, Herbelin A, Gombert JM. Eur J Immunol. 2015 Jul;45(7):1926-33. doi: 10.1002/eji.201545539. Epub 2015 May 20. PMID: 25903796
• The alarmin concept applied to human renal transplantation: evidence for a differential implication of HMGB1 and IL-33. Thierry A, Giraud S, Robin A, Barra A, Bridoux F, Ameteau V, Hauet T, Girard JP, Touchard G, Gombert JM, Herbelin A. PLoS One. 2014 Feb 20;9(2):e88742. doi: 10.1371/journal.pone.0088742. eCollection 2014. PMID: 24586382